Steroids non responder

Question regarding your dad......... I'm assuming they have him on steroids as well as anti-seizure meds... yes? It may seem simplistic, and something the docs have likely already checked, but each time I was on dexamethazone (Decadron)... I developed a diabetic response. My nurses told me that this is not that unusual, but nothing was said until I finally questioned WHY I was having the issue. They looked at me as though this was something that everyone just automatically knows! Anything I would eat, would cause a fever spike. I learned that there is sugar in just about eeeeeeeverything we put into our faces. 

Preface

Summary

1. Timeline

2. Virology

3. Transmission

4. Epidemiology

5. Prevention

6. Case Definition

7. Diagnostic Tests

8. Clinical Presentation and Diagnosis

9. SARS Treatment

10. Pediatric SARS



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9. SARS Treatment Loletta Kit-Ying SO ( Correspondence)
Arthur Chun-Wing LAU
Loretta Yin-Chun YAM The treatment of coronavirus-associated SARS has been evolving and so far there is no consensus on an optimal regimen. This chapter reviews the diverse treatment experience and controversies to date, and aims to consolidate our current knowledge and prepare for a possible resurgence of the disease.

Five patients were treated with mycophenolate mofetil for a median of 6 months. At 6-month follow up, three (60%) patients had responded to treatment. Of these, one (33%) was a responder and two (67%) were partial responders.
None of the patients on hydroxychloroquine experienced any adverse event, including no retinopathy. Three patients experienced an adverse event with the use of doxycycline. Two of these patients had a photosensitive reaction, while one experienced gastrointestinal symptoms. None of the patients reported an adverse reaction to mycophenolate mofetil.
In conclusion must be emphasized that Hydroxychloroquine is significantly effective in reducing signs and symptoms in patients with FFA and has its maximal benefit within the first 6 months of treatment.

*Side Effects of Cytomel – Hypothyroidism: There has long since been a fear of thyroid medications among many people due to the issue of hypothyroidism, which simply refers to the thyroids inability to manufacture adequate amounts of thyroid hormones. The idea is simple, synthetic thyroid mediations are used, they are discontinued and at this stage the body no longer has the ability to make its own as it has become dependent on the exogenous hormones. Many fear they will become fat and uncontrollably so due to the T3 hormone playing such an important role on the metabolism. When it comes to the side effects of Cytomel, without question this one has been blown beyond out of proportion. It would truly take massive high dose long term use to truly cause hypothyroidism in an otherwise healthy adult. The thyroid will start making its own T3 very rapidly after use is discontinued, and at a much stronger rate than say testosterone after natural testosterone has been suppressed. That aside, in order to facilitate a smooth recovery it’s not a bad idea to drop down to a low dose for a week or two before discontinuing use completely. There’s no need to ramp down, simply drop down to a low maintenance dose and then discontinue.

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Steroids non responder

steroids non responder

*Side Effects of Cytomel – Hypothyroidism: There has long since been a fear of thyroid medications among many people due to the issue of hypothyroidism, which simply refers to the thyroids inability to manufacture adequate amounts of thyroid hormones. The idea is simple, synthetic thyroid mediations are used, they are discontinued and at this stage the body no longer has the ability to make its own as it has become dependent on the exogenous hormones. Many fear they will become fat and uncontrollably so due to the T3 hormone playing such an important role on the metabolism. When it comes to the side effects of Cytomel, without question this one has been blown beyond out of proportion. It would truly take massive high dose long term use to truly cause hypothyroidism in an otherwise healthy adult. The thyroid will start making its own T3 very rapidly after use is discontinued, and at a much stronger rate than say testosterone after natural testosterone has been suppressed. That aside, in order to facilitate a smooth recovery it’s not a bad idea to drop down to a low dose for a week or two before discontinuing use completely. There’s no need to ramp down, simply drop down to a low maintenance dose and then discontinue.

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