The first branch of my group focuses on bio-analysis and bio-separations; early cancer detection by using different markers and different techniques is our major focus. Research is conducted using state-of-art instruments and techniques, such as UPLC-MS n , GC-MS, HPCE-MS, microfluidic and nanofluidic chips, and many others. In addition, single cell sensing and single molecule and single cell imaging technology has been used extensively for biomarker studies. The second branch of our research focuses on emerging environmental contaminants in natural water resources, drinking waters, and other matrices. Their impact to human health will also be investigated, such as nanotoxicity.