Therapy for Crohn's disease has been discussed in practice guidelines published in 2009 7 . These guidelines set up a definition for the severity of a Crohn's disease flare. Mild to moderate disease is indicated when patients can tolerate oral intake without dehydration, high fever, abdominal pain, abdominal mass, or obstruction. Moderate to severe disease describes the disorder in patients who have failed to respond to therapy for mild or moderate disease or those with fevers, weight loss, abdominal pain, anemia, or nausea and vomiting without frank obstruction. Severe to fulminate disease is found in patients with persisting symptoms despite the introduction of steroids on an outpatient basis or those presenting with high fever, persistent vomiting, obstruction, rebound tenderness, cachexia, or an abscess. In addition, it is important to distinguish between differing behaviors of disease: inflammatory, fistulizing, or fibrostenotic because different therapies are best suited for different disease behaviors regardless of disease severity.
Treatment of histoplasmosis depends on the severity of the clinical syndrome. Mild cases may require only symptomatic measures, but antifungal therapy is indicated in all cases of chronic or disseminated disease and in severe or prolonged acute pulmonary infection 4 ( Table 3 ) . 5 Treatment should be continued until all clinical findings have resolved and H. capsulatum antigen levels have returned to normal. 4 , 5 In patients with acquired immunodeficiency syndrome (AIDS), lifelong suppressive therapy is required to prevent relapse. 4 – 7 , 9 , 14 In immunocompetent patients with acute pulmonary disease and respiratory compromise, corticosteroids may be helpful as adjunctive therapy. 5
Q. what is "pulmonary edema" and what are the risks? my Dr. told me I'm in a risk group for pulmonary edema, he tried to explain what it is but i didn't understand fully...if someone may give me a brief explanation- I'll appreciate it! A. pulmonary edema occurs when, lets say, your heart left ventricle stops working properly and your right ventricle works fine. that means your lungs getting lets presume- 1 liter of blood -but your left ventricle can pump out of it only 990 ml. that means you have high blood pressure in your lungs and fluid comes out of blood vessels and fills your lungs, making it harder and harder breathing.