Microbial transformation of steroids pdf

Logarithmically growing bacteria differ from stationary phase bacteria with respect to the number of genome copies present in the cell, and this has implications for the capability to carry out an important DNA repair process. During logarithmic growth, two or more copies of any particular region of the chromosome may be present in a bacterial cell, as cell division is not precisely matched with chromosome replication. The process of homologous recombinational repair (HRR) is a key DNA repair process that is especially effective for repairing double-strand damages, such as double-strand breaks. This process depends on a second homologous chromosome in addition to the damaged chromosome. During logarithmic growth, a DNA damage in one chromosome may be repaired by HRR using sequence information from the other homologous chromosome. Once cells approach stationary phase, however, they typically have just one copy of the chromosome, and HRR requires input of homologous template from outside the cell by transformation. [40]

Lipases are a class of enzymes which catalyse the hydrolysis of long chain triglycerides. Microbial lipases are currently receiving much attention with the rapid development of enzyme technology. Lipases constitute the most important group of biocatalysts for biotechnological applications. This review describes various industrial applications of microbial lipases in the detergent, food, flavour industry, biocatalytic resolution of pharmaceuticals, esters and amino acid derivatives, making of fine chemicals, agrochemicals, use as biosensor, bioremediation and cosmetics and perfumery.


Mar. 7, 2018 Fleckenstein appointed Professor of Medicine on the Investigator Track and as Professor of Molecular Microbiology Read More

Nov. 21, 2017 Seven faculty are 2017 AAAS Fellows Read More

Nov. 2, 2017 Obituary: Milton J. Schlesinger, professor emeritus, 89 Read More

Oct. 26, 2017 Key malaria parasite finding could lead to new treatments Read More

Oct. 16, 2017 Hultgren elected to National Academy of Medicine Read More

August 2017 Dr. Shabaana Khader, along with Dr. Marco Colonna (Department of Pathology & Immunology) received a new NIH R01 titled “The Role of Group 3 Innate Lymphoid cells (ILC3) in Tuberculosis”

June 2017 Dr. Jennifer Lodge, along with Dr. Maureen Donlin (St. Louis University), received a new NIH R01 titled “Role of Cell Wall Integrity in Echinocandin Resistance in C. neoformans”

Dr. David Wang received a new NIH R21 titled “Recognition and signaling of viral infection in C. elegans”

Dr. Warren Lewis (in the laboratory of Dr. Amanda Lewis) received a new NIH R01 titled “Glycogen in Bacterial Vaginosis & How Carbohydrates Shape the Vaginal Microbiome”

May 8, 2017 Antibiotic resistance circumvented in lab Read More

May 4, 2017 Four Faculty elected to National Academy of Sciences Read More

May 2017 Dr. David Wang received a new NIH R61 titled “The Virome and Adverse Outcomes in Lung Transplantation”



Position Openings within Molecular Microbiology

Microbial transformation of steroids pdf

microbial transformation of steroids pdf

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