From reading this article, it should be quite easy to ascertain that clenbuterol is very precise and could be classified as “delicate” in terms of how to properly use. Clen should be cycled properly for not only safety and avoidance of short and long term side effects but that of efficacy as well. There are several possible side effects associated with clenbuterol use . Keeping all of this in mind, men should not exceed 140 mcg’s per day of clenbuterol use and women should not exceed 120. These doses should also not exceed 2 weeks of continuous use. Clenbuterol users should not use clen more than 16 weeks per calendar year. After completing a course of clen, a user should take 8-10 weeks off at the minimum although a longer rest period would be preferred.
During the two 'off' weeks, an ECA stack can be used as required. ECA will not cause such a pronounced down regulation and desensitization of the receptors, certainly not to the extent of clen. Ephedrine has a short half life in contrast to clen which results in times throughout the day where the betas will partially recover from stimulation by adrenaline and nor-adrenaline. Potency is also much weaker that that of clen, as it is not a specific agonist. Ephedrine is also thought to increase the conversion of endogenous/exogenous T4 to T3 through the activation of deiodinase enzymes responsible for this process. This is important as clen is known to slow the rate of T4 to T3 conversion. As a side note, some bodybuilders will use T3 concurrently with the Clenbuterol/ECA cutting cycle (together with certain anabolic/androgenic steroids no doubt!) in an attempt to at least maintain plasma T3 levels.