Some people experience no disadvantages after getting an injection with corticosteroids. Other people may experience pain or itching at the injection site. Other side effects are: swelling, rash and a red discoloration of the skin. A lot of people may experience headache, nausea, fluent feeling, muscle cramps, hoarse voice, hot flashes and vaginal bleeding.
An important side effect of a corticosteroid injection is that it has a negative effect on the remaining cartilage. This is the main reason that repeated injections are not first choice, although they have a very positive effect on the symptoms in a lot of people. The long term Arthrosis will worsen through these injections because the progressive cartilage wear in turn will induce new inflammation. An injection with corticosteroids is therefore an excellent bridge to (for instance) upcoming joint replacing surgery (hip or knee) but is no permanent solution for Arthrosis.